San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

The Detroit Lions visit the San Francisco 49ers on Monday at 8:15 p.m. ET, in a matchup featuring a pair of the best ...

For Lions defensive coordinator Aaron Glenn's money, 49ers star George Kittle is the best tight end in football.

Less than a year ago, the 49ers and the Lions were the two best teams in the NFC. Now the Lions are on the verge of locking up the no. 1 seed.

The Lions will face a 49ers offensive line that could be starting two tackles signed off practice squads this week ...

It's a recipe that's as versatile as it is simple. Pair it with tortilla chips, quesadillas, tacos — whatever you want on ...

David Montgomery (knee) is the only player missing from the active roster. The starting running back remains in limbo, with ...

The Lions held a 17-point lead in the NFC championship game over the San Francisco 49ers before getting outscored 27-7 in the ...