One of the simplest organic functional groups, the alkyne, offers a broad canvas for the design of cascade transformations in which up to three new bonds can be added to each of the two sterically ...

This protocol describes the catalytic asymmetric formation of all-carbon quaternary centers—a distinctive feature of many natural products and pharmaceuticals—via conjugate addition of alkylzirconium ...

Chemical groups containing oxygen, nitrogen, silicon, and other heteroatoms often react during alkene coupling reactions, generating undesirable product mixtures. But a new, iron-catalyzed radical ...

Reactions that completely break carbon-carbon double bonds have particular transformative power in synthesis. Ozonolysis, which splits one alkene into two carbonyl compounds using trioxygen, is widely ...

Chemists from the National University of Singapore (NUS) have developed a straightforward method to convert common chemicals like carboxylic acids, alcohols, and alkanes directly into valuable alkenes ...

A dilute solution of bromine is added to samples of heptane and cyclohexene. The bromination reactions and mechanisms are compared. UV light splits the bromine molecule into two reactive radicals, ...