Nature

Evaluating the performance of Bayesian and frequentist approaches for longitudinal modeling: application to Alzheimer’s disease

Linear mixed effects (LME) modelling under both frequentist and Bayesian frameworks can be used to study longitudinal trajectories. We studied the performance of both frameworks on different dataset ...
MedPage Today

Are Bayesian Statistics Coming to a Clinical Trial Near You?

The FDA's move to incorporate Bayesian statistical methods into clinical trials of drugs and biologics garnered special treatment in JAMA this week. JAMA published three perspectives -- two welcoming ...
JD Supra

Frequentist or Bayesian? All Roads Lead to Smarter Trials with FDA’s New Bayesian Guidance

Jessica Ritsick, Yifan Wang, Ph.D. Our FDA: Drug & Device Team analyzes the Food and Drug Administration’s new guidance on Bayesian approaches to innovative drug trials, providing greater clarity on ...
MedCity News

The FDA’s Bayesian Guidance Could Quietly Reshape Clinical Trial Design

New FDA guidance on the use of Bayesian statistics signals a broader shift in accommodating more flexible clinical trial ...
Nature

Using Bayes factor hypothesis testing in neuroscience to establish evidence of absence

Neuroscientists would need to know and publish whether a manipulation does not have an effect as much as whether it does. One may use drugs to block a candidate pathway. If the drug has an effect, ...