A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...

Background. A low CD4/CD8 ratio in human immunodeficiency virus (HIV)–infected individuals despite effective antiretroviral therapy (ART) reflects ongoing immune activation and has been linked to a ...

Objectives. To examine trajectories of CD8⁺ T-cell counts before and after combination antiretroviral therapy (cART) in human immunodeficiency virus (HIV)-infected individuals and associations with ...

The two-drug regimen dolutegravir/lamivudine is as effective as the three-drug regimen dolutegravir plus tenofovir ...

Prophylactic HPV vaccines prevent infection but not existing disease. A nasal nanogel vaccine shows preclinical promise for ...

Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities. As reported earlier, a chemotherapy regimen that consisted of dacarbazine, vincristine, ...

Comprehensive TK-6302 data demonstrate preclinical efficacy and safety, supporting clinical readiness, alongside established ...

In particular, CD4 counts remained low (< 200/μL for 9 months). Lymphocyte reinfusion had a significant effect on the recovery of lymphocytes, T cells, and CD8+ T cells (normalized on day 25).

Idiopathic CD4 lymphocytopenia (ICL) is a clinical syndrome that is defined by CD4 lymphopenia of less than 300 cells per cubic millimeter in the absence of any primary or acquired cause of ...

Researchers from California in the United States have conducted a study showing that important adaptive immune responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...