Opioid peptides constitute a family of endogenous and synthetic sequences that bind to classical opioid receptors—mu, delta and kappa—and modulate a range of physiological processes. Endogenous ...

Researchers at Nagoya University's Graduate School of Bioagricultural Sciences and the National Institute of Physiological Sciences in Japan have demonstrated how a specific type of neuron in the ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

A novel compound strongly improves the efficacy of naloxone, the substance used to reverse overdoses of morphine, fentanyl and other opioid drugs. When administered to mice along with naloxone, it is ...

New research could transform how we understand the way opioids affect the brain. Despite significant discussion surrounding the ongoing opioid crisis, current understanding of how opioids function in ...

As opioid overdose deaths in the U.S. rose dramatically from 2014 to today, both Philadelphia, Pennsylvania, and Camden, New Jersey, cemented reputations as hotspots of the crisis. In Philadelphia, ...