A research team led by Professor Yoosoo Yang (Department of Integrative Biotechnology) of Sungkyunkwan University, in ...
Dr. Priya Hays discusses the mechanisms of treatment resistance in cancer, highlighting their significance for developing ...
Oral cancer, predominantly oral squamous cell carcinoma (OSCC), remains a significant global health burden with high morbidity and mortality. Despite ...
Ohio State researchers have discovered that exhausted T cells collapse under the weight of misfolded proteins, activating a destructive stress response called TexPSR. Unlike normal stress systems, ...
A research team led by the Department of Clinical Oncology, Center of Cancer Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified a ...
Cancer immunotherapy has been a game-changer, but many tumors still find ways to slip past the immune system. New research reveals a hidden trick: cancer cells can package the immune-blocking protein ...
A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of Texas MD Anderson Cancer Center has uncovered a surprising mechanism of ...
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Dual action immunotherapy in CAR-T cells improves control of B-cell acute lymphoblastic leukemia progression
B-cell acute lymphoblastic leukemia (B-ALL) is the most common cancer in children, accounting for around 85% of pediatric leukemia cases. According to REDECAN, more than 400 new cases are estimated to ...
Created in BioRender.com. (a) Low neoantigen burden results in insufficient T-cell priming and activation. (b) An immunosuppressive tumor microenvironment underlies primary resistance in MSS CRC: ① ...
Findings provide mechanistic support for previously reported clinical outcomes of clinical reversal of platinum resistance/refractoriness from Phase 2 VIRO-15 trial - - Data demonstrate ...
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