To curb the spread of Lyme disease in the northeastern United States, scientists and public health experts for decades have ...

[119,120,121] OspC IgM and IgG antibodies from sera of humans with early Lyme disease were adsorbed with a seven-amino acid, carboxy-terminal OspC peptide (C7) that is conserved among infectious ...

This indicated that their OspA mRNA vaccine also had greater efficacy than an OspA protein vaccine and suggested that clinicians could develop an mRNA-based vaccine to prevent Lyme disease in humans.

Lyme disease is a bacterial infection that can spread to humans if a tick carrying the bacteria bites a person. Borrelia burgdorferi bacteria are the main cause of Lyme disease. The most common ...

The development of a vaccine for Lyme disease was intensely pursued in the 1990s. However, citing a lack of demand, the first human Lyme disease vaccine was withdrawn from the market less than 5 ...