Lyophilization, also referred to as freeze-drying, is a complex process that removes water from the drug product to preserve the product’s chemical and physical integrity. In this blog, we will ...

Freeze drying, lyophilization, and cryodesiccation are all terms used to describe the process of removing water from a sample at low temperature. This low-temperature dehydration process maximizes ...

Lyophilization is a complex operation used to prepare stable pharmaceutical and biopharmaceutical products through freeze-drying. During lyophilization, the water fraction of the product is reduced to ...

Equipment and Processing Report talked to Aridis Pharmaceuticals (San Jose, CA) to find out when spray drying might be a reasonable alternative to lyophilization. Lyophilization, or freeze drying, is ...

Developing freeze-drying processes requires patience and deep product and process understanding. Messenger RNA (mRNA) molecules are inherently unstable and readily degrade when exposed to ubiquitous ...

Approximately one-third of the unique biologicals in the FDA’s purple book are lyophilized, according to a recent paper. That includes (in 2020) nearly a quarter of monoclonal antibodies. Trends ...

This course teaches best practices in the design of lyophilization processes for biopharmaceutical products and formulations. The course describes pitfalls to avoid when designing lyophilization ...