Carolina Panthers vs Detroit Lions picks, predictions, odds, win probabilities for NFL Week 4 Sunday Night Football game on Oct. 4, 2026. Who wins?

Even the most promising teams in the NFL can have their entire season derailed by injuries. The Carolina Panthers haven't been taken out yet, but they have been bitten hard by the injury bug ever since the start of training camp.

We've identified three NFL underdogs bettors should consider in Week 4, including the Carolina Panthers against the Detroit Lions

The Carolina Panthers host the Detroit Lions at Bank of America Stadium on Oct. 4 and USA TODAY's NFL experts have locked in their picks for the action.

The 2026 NFL season is starting to take shape now that three weeks are already in the books. Detroit and Carolina are two teams that are moving in opposite directions headed into Week 4. The Lions have lived up to expectations,

Sunday Night Football in Week 4 features an intriguing NFC battle between the Detroit Lions and the Carolina Panthers.  Detroit is off to a strange start in the

NFL Week 3 continues Sunday when the Cleveland Browns host the Carolina Panthers. Start time, how to watch live, streaming and NFL TV schedule.

The SportsLine projection model, which entered Week 4 on a 54-43 run, reveals Lions vs. Panthers picks for the NFL Week 4 2026 on Sunday Night Football

A couple of key injuries to defensive starters come as a high-flying offense led by quarterback Jared Goff invades Bank of America Stadium. That should sound familiar to the Carolina Panthers, who put starting cornerbacks Jaycee Horn and Mike Jackson on injured reserve Wednesday,