SINCE the introduction of nitrogen mustard, methyl-bis-β-(chloroethyl)-amine, or HN 2 (Fig. 1), as a therapeutic agent in human cancer a number of analogues and related alkylating agents have been ...
Purpose: This phase III study compared the time to progression (TTP) of an oral regimen of dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine composed of a fixed combination of tegafur and ...
After encountering foreign antigen, B cells diversify their immunoglobulin genes by somatic hypermutation (SHM), gene conversion (GC) and class-switch recombination (CSR). SHM introduces mutations ...
Uracil in DNA may result from incorporation of dUMP during replication and from spontaneous or enzymatic deamination of cytosine, resulting in U:A pairs or U:G mismatches, respectively. Uracil ...
Back in 2010, Japan’s space agency JAXA completed one of the biggest milestones in the history of space exploration: It collected samples from an asteroid and brought them back to Earth. A decade ...
Preoperative Therapy With Trastuzumab and Paclitaxel Followed by Sequential Adjuvant Doxorubicin/Cyclophosphamide for HER2 Overexpressing Stage II or III Breast ...
Samples from the asteroid Ryugu collected by the Hayabusa2 mission contain nitrogenous organic compounds, including the nucleobase uracil, which is a part of RNA. Researchers have analyzed samples of ...
Capecitabine (Xeloda) is a fluoropyrimidine carbamate precursor of 5-FU. It is given orally and is converted via several enzymatic steps to give intratumoural release of 5-FU. The enzyme involved in ...
Copyright AD-TECH; licensee AZoM.com Pty Ltd. This is an AZo Open Access Rewards System (AZo-OARS) article distributed under the terms of the AZo–OARS https://www ...
From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or ...
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