Cells intake substances from the outside world by encapsulating them in vesicles called endosomes, which are subsequently transported throughout the cell. During the transport process, vesicles fuse ...

Researchers from the SNI network have discovered a novel way to fuse lipid vesicles at neutral pH. By harnessing a fragment of the diphtheria toxin, the team achieved vesicle membrane fusion without ...

Researchers have engineered extracellular vesicles without viral envelope proteins using pH-sensitive split inteins, ...

It takes just a few milliseconds: A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and releases its chemical messengers into the ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

A new review argues that extracellular vesicles released by Toxoplasma gondii and infected host cells act as strategic ...

For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...

Video depiction of vesicle fusion and tethering. In the active zone in the central left of the video, docked vesicles (dark blue) fuse with the membrane, releasing their contents and being quickly ...