Purpose: The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane, metered-dose inhalers (MDIs) were evaluated.Methods. Three Proventil HFA and three ...
The Ventolin HFA test MDIs also had an increased leak rate compared with controls. Upon completion of the study, the Ventolin HFA test MDIs had lost an average of 0.213 g versus 0.080 g from the ...