The Carolina Panthers face the San Francisco 49ers on Monday, Nov. 24, 2025 at Levi’s Stadium in Santa Clara, California.

The Niners are coming off a win over the Arizona Cardinals in which the offense looked full-strength with Brock Purdy and Ricky Pearsall back as Christian McCaffrey shone as a receiver.

Watch the NFL's official Week 15 game preview for Tennessee Titans vs. San Francisco 49ers. San Francisco 49ers linebacker Fred Warner joins NFL Network's "Inside Training Camp Live" to discuss defensive coordinator Robert Saleh's return to The Bay, rookies on the D-line, and tight end George Kittle crashes the interview.

Mary Kay Cabot, Ashley Bastock, Dan Labbe will go live Sunday night and get into what they saw on a live edition of the Orange and Brown Talk podcast. They’ll break down all angles of the game and spin things forward to Week 14 against the Titans. The live show will start between 8:15 and 8:30 p.m.