Healthcare around the world depends on the production of pure biopharmaceuticals. To be effective, those purification processes must be fast, robust, and affordable. By using non-affinity-based ...
Professor Kimoon Kim's research group at POSTECH has developed a highly pure and efficient technique for purifying antiviral and anti-cancer protein therapeutics using molecular affinity interaction.
Ubiquitination can have profound effects on the stability and function of cellular proteins. Mass spectrometry (MS) can be used to map the specific amino acid residues that are conjugated to ubiquitin ...
Labile, poorly expressed, or poorly soluble proteins paose many difficulties in isolation and purification. These difficulties can be overcome, however, by various means. One approach is to modify ...
Purification by affinity chromatography on immobilized calmodulin is suitable for recombinant proteins expressed in bacteria because endogenous bacterial calmodulin-binding proteins are unknown.
Antibodies are essential proteins produced by the immune system that recognize and bind to specific targets, known as antigens. Their high specificity and affinity make antibodies invaluable tools in ...
A novel method to improve the high-yield, high-purity, high-activity purification of complex proteins by 10- to 500-fold has been developed by scientists. The new method offers crucial advantages to ...
Synthetic dyes can act as alternative ligands for proteins and can be used as part of a protein purification protocol for chromatography. Chromatography is the separation of compounds from a mixture.
Previous purification methods, such as ammonium sulphate precipitation, were known to yield a crude purification of proteins. Affinity purification of antibodies is one of widely used techniques where ...
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