Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation. Most multi subunit ion channels exist in two functional states, ...

G protein-coupled potassium channels represent a critical interface between extracellular signals and electrical excitability in diverse cell types. These channels belong primarily to the inwardly ...

A group from The Mount Sinai Hospital / Mount Sinai School of Medicine have identified and characterized a novel a GIRK1-selective activator, GiGA1 capable of selectively opening a subset of G-protein ...

Scientists at the University of Kentucky have uncovered a new reason why people with Alzheimer's disease often struggle with sleep, long before memory loss begins. The study, led by researchers at the ...

This article and associated images are based on a poster originally authored by Sivakumar, M, Smith, E, Shumate, J, Scampavia, L, Spicer, T, Hernandez, D and Peters, C and presented at ELRIG Drug ...