Long-term forms of synaptic plasticity that may underlie learning and memory have been suggested to depend on changes in the number of synapses between presynaptic and postsynaptic neurons. Here we ...

Many studies link tau to synaptic dysfunction and memory loss in Alzheimer’s disease and other dementias. But how does tau do its dirty work? Most previous research focused on the harmful effects of ...

The neuron is the basic working unit of the brain, and recent studies are beginning to reveal how neurons perform the complex computations that underlie our behavior. The latest study by the National ...

Brain cells talk to each other in a variety of tones. Sometimes they speak loudly but other times struggle to be heard. For many years scientists have asked why and how brain cells change tones so ...

A model illustrating short-distance, directional vesicle transport via phase separation: a schematic diagram (upper) depicting regulated transport of vesicles from one compartment (“sub-compartment A” ...