We’ve joined many others across the research community in commenting on proposals that would give political appointees the power to decide how and where federal science funding is directed.

We share a statement and our formal comment on the White House Office of Management and Budget (OMB) revisions to guidance for federal grants and financial assistance.

Mathi Thiruppathy Peter Fabian J Andrew Gillis J Gage Crump ...

This important study provides a mechanistic view of how antibody affinity maturation can reshape encounter-state landscapes and association pathways, with implications for understanding HIV antibody ...

In this useful Tools & Resources article, the authors describe a new cryogenic light microscopy design and characterize its temperature and spatial stability. This compelling system avoids the ...

Integrating case counts with genomic sequences quantifies real-time transmission advantages of viral variants.

Extrachromosomal circular DNA has been identified as a novel component of stress granule cores, indicating its essential involvement in eukaryotic stress response pathways at the level of protein ...

The spatial organization of chromatophore-muscle innervation by motoneurons enables the generation of chromatophore-shaped noise, virtual or composite chromatophores, and shape elements such as lines ...

Some signals help the tumor grow, while others help the immune system fight back. The same signal can thus mean different things in different cells. One example is the JAK-STAT pathway. It helps cells ...

A new diffusion MRI approach offers a glimpse of the anomalies of cellular architecture underlying basal ganglia degeneration in Huntington’s disease.

Poor paternal nutrition at the time of conception shapes post-fertilisation developmental trajectory, fetal growth, and placental dynamics.

This study presents a useful methodological advance that better enables the simultaneous measurement of gene expression and chromatin accessibility in individual cells. The eviden ...