Ventolin HFA exhibited the largest change, with an 85.2% increase in respirable mass from 4 to 60°C. The respirable mass of Proventil HFA increased by 13.7% over the same temperature range.

Albuterol 90mcg/inh; metered-dose aerosol; contains hydrofluoroalkane; CFC-free. Activation of beta2-adrenergic receptors on airway smooth muscle leads to the activation of adenylcyclase and to an ...

Purpose: The effects of extreme temperatures on drug delivery of two albuterol sulfate hydrofluoroalkane, metered-dose inhalers (MDIs) were evaluated.Methods. Three Proventil HFA and three ...