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Pet hamster exposure is associated with autoimmune cerebellar ataxia: a hospital-based case–control study

Background To investigate whether exposure to pet hamsters may act as a potential trigger for autoimmune cerebellar ataxia (ACA). Methods We conducted a hospital-based case–control study based on our ...
Journal of Neurology, Neurosurgery and Psychiatry (JNNP)Opinion

Is it time for the removal of valproate restrictions in men? Further evidence from a new study

In a population-based cohort study by Razaz et al ,1 risks of neurodevelopmental disorders in 2051 children of fathers taking ...
BMJ

053 Brainshuttle AD: Investigating safety, tolerability, and PK/PD of RG6102 in prodromal/mild-to-moderate AD

RG6102 is a bispecific 2+1 monoclonal antibody (mAb) under development for the treatment of Alz- heimer’s disease (AD). It combines the anti-amyloid beta antibody gantenerumab with a transferrin ...
BMJ

Long-term functional decline of spontaneous intracerebral haemorrhage survivors

Correspondence to Professor Didier Leys, Neurology, Stroke Unit, University of Lille, Lille 59000, Hauts-de-France, France; didier.leys{at}univ-lille.fr Objective To identify in patients who survived ...
BMJ

Circadian rhythm of ischaemic core progression in human stroke

Introduction Experimental stroke studies suggest an influence of the time of day of stroke onset on infarct progression. Whether this holds true after human stroke is unknown, but would have ...
BMJ

Critical closing pressure in cerebrovascular circulation

a Wolfson Brain Imaging Centre, MRC Cambridge Centre for Brain Repair and Academic Neurosurgical Unit, b Department of Anaesthesia and The Neurosciences Critical Care Unit, Addenbrooke’s Hospital, ...
BMJ

Coughing and choking in motor neuron disease

a Department of Medicine (Neurology), University of Wales College of Medicine, Cardiff, UK, b The Common Cold Centre, Cardiff School of Biosciences, Cardiff University, UK Dr S Hadjikoutis, Department ...
BMJ

Short delay to initiate plasma exchange is the strongest predictor of outcome in severe attacks of NMO spectrum disorders

Introduction Severe attacks of neuromyelitis optica spectrum disorder (NMO-SD) are improved by plasma exchange (PLEX) given as an adjunctive therapy. Initial studies failed to demonstrate a delay of ...
BMJ

Diagnostic challenges in hereditary transthyretin amyloidosis with polyneuropathy: avoiding misdiagnosis of a treatable hereditary neuropathy

6 Amyloidosis Research and Treatment Center, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy Correspondence to Professor Giampaolo Merlini, Amyloidosis Research and Treatment Centre, IRCCS ...
BMJ

Unilateral frontal lobectomy can produce strategy application disorder.

Following a 5 cm left frontal lobectomy for the removal of a mixed astrocytoma-oligodendroglioma, a 51 year old right handed man showed a marked dissociation between his performance on standard ...
BMJ

Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy

Correspondence to Dr Shigeaki Suzuki, Department of Neurology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan; sgsuzuki{at}z3.keio.jp Objective To elucidate ...