The San Francisco 49ers announced they have signed QB Mac Jones to a two-year deal. Jones (6-3, 200) was originally drafted ...

The 49ers lost a large contingent of household names that helped them dominate the NFC for the last five-plus years, ...

The San Francisco 49ers' roster overhaul continues with the release of long snapper Taybor Pepper, ending his five-season ...

Residents and politicians are at odds over what to name the long-awaited sports complex and park being built in southeast ...

The San Francisco 49ers today announced that the team has re-signed LB Curtis Robinson to a one-year deal.

Protein design (or protein engineering) is a technique by which proteins with enhanced or novel functional properties are created. Proteins can be engineered by rational design, which typically ...

Jimmy Johnson, the Pro Football Hall of Fame coach who won two Super Bowls and a college national championship, announced his ...

The San Francisco 49ers haven't drafted an offensive lineman since taking Notre Dame's Aaron Banks in the second round in 2021. That could change this April. The 49ers are evaluating tons of ...

INDIANAPOLIS -- The 49ers could lose Jordan Mason this offseason. Mason will be a restricted free agent when the new league year starts and the 49ers haven't decided what to do with him.

49ers GM John Lynch provides updates on Brock Purdy, Deebo Samuel, and the injury status of stars Christian McCaffrey and Trent Williams. (Shutterstock) 49ers GM John Lynch provides updates on Brock ...

San Francisco 49ers General Manager John Lynch swiftly put to rest retirement rumors surrounding All-Pro left tackle Trent Williams. Lynch spoke, saying that he is “ready” and “motivated ...

Despite all those trials and tribulations, San Francisco 49ers general manager John Lynch revealed at the NFL combine that Williams will return to the team in 2025. Lynch described the 36-year-old ...