The treatment of metastatic hormone-sensitive prostate cancer (mHSPC) has evolved in recent years towards combination therapy, enhancing survival outcomes when compared with androgen deprivation ...

Membrane receptors and transporters translate extracellular cues into cellular responses by harnessing conformational changes, ion flux or enzymatic activity. Fast-acting ligand-gated ion channels ...

Hormone therapy (HT), also known as hormone replacement therapy (HRT), can cause hair loss in some people, but not everyone experiences this side effect. Hair loss from HT often appears as gradual ...

In their study, Brown et. al. provide an important advance in understanding the architecture of the mycobacterial outer membrane. Using all-atom simulations of model mycomembranes, the work reports ...

The interaction between sphingomyelin (SM) and cholesterol, two of the most abundant lipids in plasma membranes of animal cells, provides many functional benefits. These include protection from ...