San Francisco 49ers quarterback Brock Purdy exited Monday night's shootout with the Detroit Lions in the final two minutes, as the Niners were driving for a late touchdown to cut the Lions' lead to ...

Jennifer Lee Chan shares the latest injury report for Sunday's San Francisco 49ers vs. Arizona Cardinals game.

The stage is set for the biggest regular season game in NFL history as the Detroit Lions take on the Minnesota Vikings on ...

Detroit Lions offense excelled against San Francisco 49ers. Wayne Osmond, founding member of the Osmonds, is dead at 73 ...

Former Pittsburgh Steelers quarterback Josh Dobbs will start for the San Francisco 49ers in their game against the Arizona ...

Detroit Lions offensive tackle Penei Sewell has been selected to his third consecutive NFC Pro Bowl roster, but the former Oregon Ducks unanimous All-American s ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's season finale against the Arizona Cardinals due to a right ...

The San Francisco 49ers came out swinging against the Detroit Lions in Week 17, taking a 21-13 lead into halftime. However, the Lions pounced in the second half, putting up 27 points to complete a ...

Detroit Lions safety Kerby Joseph was apparently unhappy about being passed over for this year's NFC Pro Bowl team, so he ...

San Francisco 49ers head coach Kyle Shanahan announced on Wednesday that Josh Dobbs would start this weekend in place of an ...

Josh Dobbs’ first start with the 49ers in the regular-season finale against the Arizona Cardinals comes at the end of a slow-paced season for the San Francisco quarterback.

Gibbs has taken the workhorse role in the first two games without Montgomery and run with the opportunity. He has back-to-back games with 100-plus rushing yards, and has continued to be a receiving ...