The San Francisco 49ers have been struggling with injuries all season, and it finally caught up with them. On Sunday, they lost 26-15 to the Houston Texans.

Houston held Christian McCaffrey to 68 yards with a plan that started up front and also included the Texans' offense.

Although this is the 49ers' third loss of the season, their Week 8 defeat to the Houston Texans should raise some alarm bells. The season is by no means over. With a 5–3 record, the 49ers are still in a favorable position,

The Seattle Seahawks (5-2) triumphed 27-19 over the Houston Texans (2-4) in a game that wasn't as close as the scoreboard indicated. Seattle struggled to get out of their own way, committing four turnovers -- their most in a game since 2020.

The Houston Texans jumped on the San Francisco 49ers early in an impressive bounce-back performance Sunday at NRG Stadium in Houston. The Texans’ 26-15 win was their first over San Francisco since 2009.

At halftime, Houston held a 16-3 lead over the 5-2 49ers, as the Texans’ offense had outgained San Francisco 326 yards to just 72. Houston entered the game at 2-4 but has looked far sharper in front of its home crowd, finding rhythm behind an efficient passing attack and steady defensive pressure.

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The key is Jones beating the pass rush. The Houston defense is built around its front four getting pressure. Take that away and the 49ers can build long sustained drives and convert in the red zone against this defense. McCaffrey should have success on the ground, but could be limited in the air.

The Texans arguably played one of their better games of the season and Houston's Week 8 report card reflects that.

The San Francisco 49ers (5-2) visit the Houston Texans (2-4) Sunday in Week 8. Kickoff from NRG Stadium in Houston, Texas, is at 1 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NFL odds around the 49ers vs. Texans odds and make our expert NFL picks and predictions for the best bets.

San Francisco fans seemed to flood NRG Stadium in a large showing for the Week 8 game, according to videos and photos shared on social media by local reporters and fans present at the stadium. The kickoff at Noon CT showed plenty of 49ers' scarlet and gold. Houston's "battle red" and "deep steel blue" was more scattered throughout the stadium.