Texans head coach DeMeco Ryans is a former 49ers defensive coordinator under Kyle Shanahan, so San Francisco knows how ...

The 49ers had the ball for only 18 ½ minutes Sunday. It's an apt analogy for Mac Jones, whose time as San Francisco's ...

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs.

San Francisco 49ers quarterback Mac Jones locates tight end George Kittle for a 17-yard sliding grab against the Houston ...

ESPN BET Sportsbook is owned and operated by PENN Entertainment, Inc. and its subsidiaries ('PENN'). ESPN BET is available in ...

Mac Jones has been a massive addition to the San Francisco 49ers this offseason. The team is 4-1 when he starts this season, ...

Mac Jones will again be the starting quarterback for the San Francisco 49ers after Brock Purdy was ruled out of Sunday's game ...

Team president of football operations and general manager John Lynch shared encouraging news about Purdy’s recovery during an ...

Brock Purdy's injury update opens a financial opportunity for San Francisco 49ers backup quarterback Mac Jones.

San Francisco 49ers quarterback Brock Purdy has been ruled out for his team's Week 8 matchup against the Houston Texans amid ...

Talking to NBC Sports Bay Area's Matt Maiocco, San Francisco coach Kyle Shanahan shared what Mac Jones has to do for the ...

The 49ers' are dealing with more injuries ahead of their Week 8 matchup versus the Texans. This features Brock Purdy and ...