Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs.

The San Francisco 49ers have been winning games with the next man up mentality. They have been able to get by with the depth ...

The San Francisco 49ers will face the Houston Texans in Week 8 of the NFL season on Sunday at NRG Stadium.

When the San Francisco 49ers finally picked up a first down Sunday against the Houston Texans they were already down by 16 ...

For the first time in nearly a year, the 49ers defense has notched an interception, ending an NFL record-long drought.

The San Francisco 49ers will need their secondary at full strength to combat injuries on the defensive line vs. the Houston ...

The Texans arguably played one of their better games of the season and Houston's Week 8 report card reflects that.

George Kittle still believes the San Francisco 49ers have the "right guys" with the NFL trade deadline looming after the loss ...

The NFL season continues when the Houston Texans host the San Francisco 49ers Sunday. Start time, how to watch, streaming and ...

The San Francisco 49ers entered their Week 8 matchup against the Houston Texans as favorites and lost. Here were the worst ...

The San Francisco 49ers are used to playing shorthanded, but this week they will also face a foe that is coming in without ...

The San Francisco 49ers (5-2) visit the Houston Texans (2-4) Sunday in Week 8. Kickoff from NRG Stadium in Houston, Texas, is ...