1 Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA 2 ...

Background/aim Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are rare imprinting disorders caused by the aberrant expression of 15q11.2-q13 imprinted genes. Due to their rarity, data on ...

Maria Valentina Abate, Ingeborg Barisic, Michele Santoro, Alessio Coi, Joachim Tan, Ester Garne, Maria Loane, Ljubica Odak, Elisa Ballardini, Clara Cavero-Carbonell ...

Objectives Primary: To evaluate the diagnostic accuracy of point-of-care ultrasound (POCUS) in the diagnosis of appendicitis in paediatric patients presenting with suspected appendicitis. Secondary: ...

Identifying a genetic cause for growth disorders is crucial for detecting multi-system conditions, determining eligibility or contraindications for growth therapies and ending the diagnostic odyssey.

Correspondence to: Prof. H P van Bever Department of Paediatrics, National University Hospital, Singapore, 5 Lower Kent Ridge Road, Singapore 119074; paevbhpsnus.edu.sg If you wish to reuse any or all ...

Introduction We aimed to establish the clinical characteristics of children and young people (CAYP) currently receiving deep brain stimulation (DBS) therapy for the management of movement disorders in ...

Background In Europe, 50%–60% of pregnant women uses paracetamol (Dafalgan). While its use in pregnan-cy was considered safe, recent studies show an associ-ation between prenatal exposure to ...

Since the onset of the COVID-19 pandemic, paediatricians and child mental health practitioners have noticed an increase in tic symptoms in some children and adolescents already diagnosed with tic ...

Objective To determine if an age-appropriate intervention is more effective than treatment as usual (TAU) in reducing post-traumatic stress disorder (PTSD) symptoms in parents/guardians of children ...

Objective To determine the safety of ciprofloxacin in paediatric patients in relation to arthropathy, any other adverse events (AEs) and drug interactions. Methods A systematic search of MEDLINE, ...

Each year hundreds of randomised controlled trials are conducted in low- and middle-income countries addressing issues in clinical paediatrics and in child and adolescent health. The topics are as ...