Background The life-long exposure of the left heart chambers to systemic blood pressures may be important to changes in left ...

Background Since the 1960s, beta blockers have been used to treat hypertrophic obstructive cardiomyopathy (HOCM), a genetic ...

Background Pocket haematoma is a common complication of cardiac implantable electronic device (CIED) procedures and may lead ...

Background The minimally important difference (MID) for frailty variation associated with adverse outcomes remains unknown in ...

Background We aimed to estimate mental disorder disparities in cardiovascular disease (CVD) incidence and determine whether ...

Background Many observational studies highlight clonal haematopoiesis (CH) as a novel determinant of cardiovascular disease ...

Objective To clarify whether atherogenic index of plasma (AIP), a comprehensive indicator reflecting both the protective and ...

Background Revised haemodynamic criteria for pulmonary hypertension (PH)—mean pulmonary artery pressure (mPAP) >20 mm Hg and pulmonary vascular resistance (PVR) >2 Wood Units (WU)—have defined new ...

Upregulated transforming growth factor-beta (TGFβ) signalling, driving mesenchymal cells to increase their production of ground substance and undergo a transition to a myofibroblast phenotype, is ...

Background Biochemical markers of inflammation, coagulation and myocardial stress have been associated with both prevalent and incident atrial fibrillation (AF), but little is known about the ...

Background Hospitalisation with acute heart failure (AHF) carries a high risk of death, and those surviving to discharge remain at high risk of death or rehospitalisation with AHF. The impact of ...

Background Postoperative cerebral infarction following coronary artery bypass grafting (CABG) for multivessel coronary artery disease (CAD) is a major complication and is associated with insulin ...