Objectives The oral microbiome plays a critical role in modulating systemic inflammation, partly through its interactions ...

Objective Idiopathic inflammatory myopathies (IIM) are a heterogenous group of conditions with substantial morbidity but ...

Objective The primary objective was to assess sex differences in long-term functional deterioration and permanent work ...

Objective To evaluate the diagnostic pathway of patients affected by large vessel vasculitis (LVV) and to determine factors ...

Systemic sclerosis (SSc) is a rare, heterogeneous, systemic autoimmune rheumatic disease characterised by vasculopathy, ...

Objectives Eosinophilic granulomatosis with polyangiitis (EGPA) is classified as a subtype of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). A recent genome-wide association ...

Objective Sarcopenia, defined by reductions in muscle mass and strength, increases the risk of adverse outcomes in patients with rheumatoid arthritis (RA)—driven in part by chronic inflammation—and is ...

In this systematic review and individual participant data meta-analysis, low-dose glucocorticoids, taken over 2 years to treat rheumatoid arthritis, had a small but statistically significant impact on ...

Background Renal involvement in ankylosing spondylitis (AS) is recognised but understudied, with heterogeneous reports ranging from urinalysis abnormalities to end-stage disease and malignancy. Robust ...

Objective This multicentre randomised controlled trial aimed to compare the efficacy and safety of iguratimod (IGU) and hydroxychloroquine (HCQ) in patients with active primary Sjögren’s syndrome (pSS ...

Objective To assess the long-term effect of bimekizumab, a dual inhibitor of IL-17A and IL-17F, on patient-reported symptoms, function and health-related quality of life (HRQoL) in patients with axial ...

Objective To investigate the prevalence of difficult-to-treat psoriatic arthritis (D2T-PsA) and classify patients with persistent inflammatory PsA (PIPsA) and non-inflammatory PsA (NIPsA) based on a ...