📌Clinical Guide: Torsades de Pointes (TdP) & Long QT Syndrome (LQTS) --- Key Causes 1. Drug-Induced QTc Prolongation: - High-risk agents: Amiodarone, fluoroquinolones, macrolides, SSRIs, antipsychotics, antiemetics. 2. Electrolyte Imbalances: Hypokalemia, hypomagnesemia. 3. Inherited LQTS: LQTS1/2/3 mutations (confirm via genetic testing). Diagnosis - ECG: QTc ≥460 ms (women) / ≥450 ms (men). - Indeterminate Cases: Holter monitor, exercise stress testing. Acute TdP Management 1. Immediate Actio
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📌Clinical Guide: Torsades de Pointes (TdP) & Long QT Syndrome (LQTS) --- Key Causes 1. Drug-Induced QTc Prolongation: - High-risk agents: Amiodarone, fluoroquinolones, macrolides, SSRIs, antipsychotics, antiemetics. 2. Electrolyte Imbalances: Hypokalemia, hypomagnesemia. 3. Inherited LQTS: LQTS1/2/3 mutations (confirm via genetic testing). Diagnosis - ECG: QTc ≥460 ms (women) / ≥450 ms (men). - Indeterminate Cases: Holter monitor, exercise stress testing. Acute TdP Management 1. Immediate Actio
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Sorry this is a longer one so stick with me… Over the last 10 years, there have been incredible advancements in the understanding and treatment of Long QT Syndrome. There’s more awareness, new research, and even the first therapies designed specifically for Long QT now on the horizon @thryvtrx . All of that gives me hope for families facing the same terrifying uncertainty we once did. But what makes me most proud is the shift toward recognising that life with Long QT is not just about survival —
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