Cardiac Effects of Antipsychotics: QTc Prolongation
Cardiac Effects of Antipsychotics: QTc Prolongation
Jul 18, 2019
psychopharmacologyinstitute.com
📌Clinical Guide: Torsades de Pointes (TdP) & Long QT Syndrome (LQTS) --- Key Causes 1. Drug-Induced QTc Prolongation: - High-risk agents: Amiodarone, fluoroquinolones, macrolides, SSRIs, antipsychotics, antiemetics. 2. Electrolyte Imbalances: Hypokalemia, hypomagnesemia. 3. Inherited LQTS: LQTS1/2/3 mutations (confirm via genetic testing). Diagnosis - ECG: QTc ≥460 ms (women) / ≥450 ms (men). - Indeterminate Cases: Holter monitor, exercise stress testing. Acute TdP Management 1. Immediate Actio
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📌Clinical Guide: Torsades de Pointes (TdP) & Long QT Syndrome (LQTS…
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FacebookAbdallah Othman
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6 Common Drugs That Prolong the QT Interval! 📉⚡️ | CBS Synapse
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Classify Rx on Instagram: "Unique Characteristics Within Their Class ⚡ Palonosetron (5-HT3 Antagonist) - No QT Prolongation 📍 Class effect: Other 5-HT3 antagonists (ondansetron, granisetron, dolasetron) prolong QT interval - can cause torsades de pointes 📍 Exception: Palonosetron does NOT prolong QT interval - structurally different with unique binding, safer cardiac profile despite being in same class ⚡ Tenofovir - Nucleotide RTI (Not Nucleoside) 📍 Class terminology: Tenofovir is an nRTI (nu
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Instagramsimplify.drugs
Many psychotropic medications can prolong QTc, often without obvious symptoms. Cardiac history, electrolyte imbalances, age, and medication stacking can quietly raise arrhythmia risk. Our role goes beyond prescribing. We need to know who is at risk, what to monitor, and when a referral is no longer optional. #pmhnpstudent #npstudent #pmhnp #psychnpstudent #qtc
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